Teaching module description
03.10.2019
Teaching module description
Name of module (course) |
BIOCHEMISTRY |
Code |
ZBC |
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Field of study |
dentistry |
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Profile |
general academic |
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Level of studies |
long-cycle studies |
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Specialisation |
- |
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Mode of studies |
full-time studies |
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Semester |
III |
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Classes in the realm of basic sciences |
YES |
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Form of approval |
exam |
ECTS credit 6 |
Evaluation form |
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Form of study |
Study hours |
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Total |
Self-study |
Contact hours |
Teaching effects verification form |
% |
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Lecture |
30 |
10 |
20 |
Test |
60 |
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Seminar |
50 |
30 |
20 |
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Practical classes |
80 |
30 |
50 |
Continuous observation, practical statement |
30 |
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Self-study |
20 |
20 |
0 |
Preparation of materials and presentations |
10 |
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Total: |
180 |
90 |
90 |
Total |
100 % |
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Effects category |
No. |
Teaching effects for the course module |
Teaching effect verification form |
Field effect code |
Area effect code |
Notes |
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Knowledge |
1. |
knows the importance of major and trace elements in the processes occurring in the body, including the supply, absorption and transport |
test |
B.W.1 |
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2. |
knows the biochemical basis of the integrity of the human body |
test |
B.W.3 |
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3. |
knows the structure and functions of the major compounds present in the human body, in particular, the characteristics, functions, and energy metabolism reaction: proteins, nucleic acids, carbohydrates, lipids, enzymes and hormones; |
test |
B.W.4 |
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4. |
knows the role and significance of body fluids including saliva |
test |
B.W.6 |
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5. |
vital functions |
test |
B.W.19 |
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6. |
knows the principles of acid-base balance and the transport of oxygen and carbon dioxide in the body |
test |
B.W.21 |
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7. |
knows the principles of metabolism and nutrition |
test |
B.W.22 |
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Skills |
1. |
refers to the phenomenon of chemical processes occurring in the oral cavity; |
practical statement |
B.U.1 |
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2. |
use of biological and ecological concepts in the context of a man - living environment |
practical statement |
B.U.4 |
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Teachers
Form of study |
Course teachers |
Lecture |
Prof. dr hab. n. med. Sławomir Kasperczyk, dr hab. n. med. Jolanta Zalejska-Fiolka, dr n. med. Urszula Błaszczyk, dr n. med. Ewa Romuk, dr hab. Michał Dobrakowski, dr hab.n.med. Aleksandra Kasperczyk |
Seminars |
Prof. dr hab. n. med. Sławomir Kasperczyk, dr hab. n. med. Jolanta Zalejska-Fiolka, dr n. med. Urszula Błaszczyk, dr n. med. Ewa Romuk, dr hab. Michał Dobrakowski, dr hab.n.med. Aleksandra Kasperczyk |
laboratory |
Prof. dr hab. n. med. Sławomir Kasperczyk, dr hab. n. med. Jolanta Zalejska-Fiolka, dr n. med. Urszula Błaszczyk, dr n. med. Ewa Romuk, dr hab. Michał Dobrakowski, dr hab.n.med. Aleksandra Kasperczyk |
Course contents
Lecture |
Semester III |
Teaching methods |
Lecture |
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No. |
Topics |
Hours |
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1. |
Fundamentals of general and clinical enzymology. |
2 |
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2. |
Electron Transport Chain and Krebs cycle. |
2 |
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3. |
Carbohydrates metabolism part 1. The main pathways of carbohydrate, energetics. |
2 |
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4. |
Carbohydrates metabolism part 2. Disorders of carbohydrate metabolism, diabetes mellitus |
2 |
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5. |
Lipid metabolism part 1. Transport and storage of lipids. Biosynthesis and oxidation of saturated and unsaturated fatty acids; unsaturated fatty acid metabolism.. |
2 |
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6. |
Steroids biochemistry. Synthesis, transport and excretion of cholesterol. Bile acids. |
2 |
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7. |
Metabolism of aminoacids, peptides and proteins |
2 |
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8. |
Metabolism of nucleotides |
2 |
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9. |
Structure of nucleic acids and expression of genetic information. |
2 |
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10. |
Oxidative stress |
2 |
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Hours total: |
20 |
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Seminars |
Semester III |
Teaching methods |
The teacher introduction, student presentations and discussion |
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No. |
Topics |
Hours |
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1. |
Fudamentals |
2 |
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2. |
Building, structure and function of peptides, proteins and enzymes. |
2 |
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3. |
Tissue oxidation, phosphorylation, the Krebs cycle. |
2 |
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4. |
Metabolism of carbohydrates. |
2 |
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5. |
Lipid metabolism. |
2 |
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6. |
Steroids biochemistry. Metabolism of cholesterol. |
2 |
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7. |
Metabolism of proteins, proteolytic enzymes. Metabolism of selected amino acids. |
2 |
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8. |
The metabolism of purine and pyrimidine nucleotides. Biosynthesis of the protein. |
2 |
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9. |
Colloquim |
4 |
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Hours total: |
20 |
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Practical classes |
Semester III |
Teaching methods |
The theoretical introduction and practical exercises on biological material, the interpretation of the results, reasoning |
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No. |
Topics |
Hours |
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1. |
Safety in laboratory. Fundamentals in biochemistry. |
5 |
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2. |
Characteristics and metabolism of plasma and serum proteins with particular reference to acute phase proteins. Methods for separation and analysis of proteins. |
4 |
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3. |
Enzymology: - Structure and properties of the enzymes. - Methods for the enzymes classification with particular emphasis on the division of the enzyme. - Kinetics of enzymatic reactions, the factors affecting the rate of enzymatic reactions including inhibition. - Methods for the determination of enzyme activity (spectrophotometry, kinetic methods). - Determination of enzymes: amylase, transferase, phosphatase. - Introduction to the enzyme laboratory diagnostics. |
16 |
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4. |
Carbohydrate metabolism: - Characteristics of carbohydrates. - Glucose homeostasis. - Hyperglycemia and glycation of proteins. - Hypoglycemia. - Methods for the determination of glucose and glycated hemoglobin in the blood. |
5 |
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5. |
Protein-nitrogen and urea: - The importance of the urea cycle and the diagnostic role of urea. - Hyper and hypoazotemics. - Methods for the quantitative determination of urea. |
4 |
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6. |
Creatinine and uric acid: - Biosynthesis and the role of creatine and phosphocreatine. - Creatinine as diagnostics factor. - Biosynthesis and the role of uric acid. - Hyperuricemia. - Methods for the determination of creatinine and uric acid in serum and urine. |
4 |
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7. |
Saliva and Teeth: - Production of saliva. - Organic and inorganic components of saliva. - Buffer capacity of saliva. - The function of the digestive, secretory, and excretory salivary defense. - Anatomical structure and chemical composition of teeth. - Deposits of teeth engaging formations. - Caries. - Biochemical methods for determining pH and organic and inorganic components of saliva. |
4 |
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8. |
Isolation of RNA from yeast |
4 |
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9. |
RNA determination Determination of ribose in RNA of yeast Detection of purines |
4 |
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Hours total: |
50 |
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Self-study |
Teaching methods |
Expanding knowledge through search and familiarity with current information on the subject of the object. Strengthening the knowledge on the basis of an independent analysis of the available sources. (Source: Internet, scientific journals, books) |
Basic literature
1. |
Lippincott’s Illustrated Reviews Richard A. Harvey |
2. |
Harper Biochemistry – Murray R.K., Granner D.K., Mayes P.A., Rodwell V.W., PZWL Warsaw |
Supplementary literature
1. |
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko. PWN, Warsaw. Biochemistry. |